Tony Todd established a significant career as a voice actor in animation and video games, bringing his famously deep and resonant voice to numerous genre projects. While he was not a voice actor in traditional Japanese anime, he had a notable presence in Western animation, often in series with styles influenced by anime, and he performed in animated productions tied to Japanese franchises. His voice work in this area includes providing the voice for Dreadwing, a Decepticon jet, in the animated series Transformers: Prime. Additionally, he voiced the character Slyrak in the Netflix animated series Dota: Dragon's Blood, which is based on a popular video game and produced in an anime style. Beyond these specific titles, Todd's prolific voice acting career encompassed a wide range of roles in other animated series and video games, often collaborating within the science fiction and fantasy genres. He voiced the ancient Decepticon known as The Fallen in the live-action film Transformers: Revenge of the Fallen. He was also the voice of the supervillain Zoom in The Flash television series and Darkseid in several films within the DC Animated Movie Universe. In the realm of video games, his notable achievements include voicing Venom in Marvel's Spider-Man 2, a performance that earned him a nomination for a British Academy Games Award.