Reina Takeshita is a Japanese voice actress born on July 20, 1989, and hails from Kagoshima Prefecture. She is affiliated with the agency LEOPARD STEEL and is a graduate of the 18th class of the Shoto ACTORS GYMNASIUM training program. She is known to have an interest in dance and film appreciation, with skills that include memorizing scripts and singing.

Takeshita began her career in the early 2010s, with some of her first roles being minor characters in anime series such as Eccentric Family and Photo Kano in 2013. She is perhaps best recognized for two specific roles from the mid-2010s. She voiced Kurō Ōtani in the 2015 comedy series Komori-san Can't Decline, a role that brought her some early visibility. The same year, she was cast as Ikue Usami in the romantic comedy series Momokuri, which first premiered on a mobile app in 2015 before a wider television release.

Her career in the mid-2010s saw her cast in a variety of supporting parts across numerous anime series. In 2015, she appeared in The Knight in the Area, Lance N' Masques, and had a role in Actually, I Am. The following year, 2016, was particularly active for her. In addition to her role in Momokuri, she provided voices for characters in And you thought there is never a girl online?, Bakuon!!, and Kiss Him, Not Me.

In the years that followed, she continued to take on minor and supporting character roles. Her more recent credits include a role as a child in Shadowverse Flame in 2023 and as a nurse in the globally popular series Solo Leveling in 2024. She also contributed to the 2019 theatrical anime film Hello World.

While information on specific recurring creative collaborations with directors or studios is not readily documented, her body of work consists largely of ensemble casts. Takeshita's career has been consistently active, though she has not yet become widely known for headlining major franchises, with her roster consisting primarily of supporting or less prominent characters across roughly a dozen productions. There is no readily available information regarding major industry awards or other forms of formal recognition for her voice acting work at this time.