"Manga Hajimete Omoshiro Juku" is an educational anime series designed to introduce viewers to the fundamentals of manga creation. The narrative centers around a group of students who enroll in a specialized school, Omoshiro Juku, to learn the art of manga. Each episode focuses on a specific aspect of manga production, such as character design, storytelling, panel layout, and inking techniques. The students, guided by their experienced instructors, tackle various challenges and assignments that help them develop their skills and understanding of the craft.

The main characters include a diverse group of students, each with unique personalities and artistic styles. Their interactions and collaborations highlight the collaborative nature of manga creation. The instructors, seasoned professionals in the manga industry, provide practical advice and insights, often drawing from their own experiences. The series balances educational content with lighthearted moments, showcasing the students' growth and the occasional mishaps they encounter along the way.

Throughout the series, the students work on individual and group projects, culminating in the creation of their own manga. These projects serve as a practical application of the lessons learned, allowing the characters to experiment with different genres and techniques. The narrative emphasizes the importance of perseverance, creativity, and teamwork in overcoming the challenges of manga production. By the end of the series, the students have not only improved their technical skills but also gained a deeper appreciation for the art form and the effort required to produce a compelling manga.