"The Café Terrace and Its Goddesses" centers around Hayato Kasukabe, a young man who inherits a seaside café from his late grandmother. Upon returning to his hometown, he discovers that the café is being managed by five unique and spirited young women, each with distinct personalities and backgrounds. These women—Ouka Shirosaki, Riho Tsukishima, Ami Tsuruga, Akane Hououji, and Mao Natsukawa—have formed a close-knit bond while running the café, but their dynamic is disrupted by Hayato’s arrival.

The narrative explores the challenges of managing the café while balancing the interpersonal relationships among the group. Hayato, initially reluctant to take on the responsibility, gradually becomes invested in the café’s success and the lives of the women. Each of the five "goddesses," as they are often referred to, has her own motivations and struggles, which are revealed through the series. Ouka is pragmatic and hardworking, Riho is cheerful and optimistic, Ami is reserved and artistic, Akane is bold and assertive, and Mao is gentle and nurturing. Their interactions with Hayato and each other drive much of the story’s development.

As the series progresses, the group faces various obstacles, including financial difficulties, rival businesses, and personal conflicts. The café serves as a central hub for both comedic and heartfelt moments, blending slice-of-life elements with light romantic undertones. The story also delves into the characters’ pasts, uncovering their connections to Hayato’s grandmother and the reasons they chose to stay at the café. Themes of family, friendship, and personal growth are woven throughout the narrative, creating a balance of humor, drama, and emotional depth. The series ultimately portrays the journey of six individuals learning to coexist, support one another, and find purpose in their shared endeavor.