"Panpaka Pantsu O NEW-san" is a short-form anime series that centers around the daily lives and humorous misadventures of a group of anthropomorphic animals living in a whimsical, lighthearted world. The main character, NEW-san, is a cheerful and somewhat naive penguin who often finds himself in comical situations due to his clumsiness and overly optimistic nature. He shares his home with a diverse cast of characters, including Pantsu, a mischievous and energetic rabbit who serves as NEW-san's best friend and frequent partner in chaos. Other notable characters include Gachapin, a curious and playful dinosaur, and Mukku, a shy and gentle bear who often provides a calming presence amidst the group's antics.

The series is episodic, with each short episode focusing on a self-contained story that highlights the characters' interactions and their unique personalities. The humor is largely derived from slapstick comedy, exaggerated reactions, and the absurdity of the situations the characters find themselves in. Despite their differences, the group shares a strong bond, and their adventures often emphasize themes of friendship, teamwork, and the importance of embracing life's quirks. The tone is consistently light and family-friendly, making it accessible to a wide audience. The simplicity of the narrative and the charm of the characters contribute to the series' appeal as a quick, enjoyable watch.