"Panty Flash Teacher" centers around Kintaro Oe, a brilliant and highly educated individual who holds multiple advanced degrees, including a PhD from Harvard. Despite his academic achievements, Kintaro chooses an unconventional path, working as a substitute teacher at an all-girls high school. His unorthodox methods and eccentric personality often clash with the school’s administration and societal norms, but his genuine care for his students and his ability to solve their personal and academic problems earn him their respect and admiration.

The series explores Kintaro’s interactions with the students and staff, highlighting his unique approach to teaching and problem-solving. Each episode typically revolves around a specific student or group of students facing challenges, ranging from academic struggles to personal dilemmas. Kintaro’s solutions often involve unconventional tactics, blending his vast knowledge with a deep understanding of human nature. His methods, while effective, frequently push the boundaries of propriety, leading to humorous and sometimes controversial situations.

Key characters include Kintaro himself, whose intelligence and eccentricity drive much of the narrative; the school’s headmistress, who often finds herself at odds with Kintaro’s methods but acknowledges his results; and various students, each with distinct personalities and issues that Kintaro helps resolve. The series balances comedy with moments of heartfelt drama, as Kintaro’s interventions often lead to personal growth for the students and a deeper understanding of their own potential.

The narrative structure is episodic, with each installment focusing on a new challenge or student, while maintaining an overarching thread of Kintaro’s impact on the school community. The series blends humor, drama, and occasional social commentary, creating a dynamic and engaging viewing experience. Through its exploration of education, personal development, and the complexities of human relationships, "Panty Flash Teacher" offers a unique take on the school-life genre, anchored by its charismatic and unconventional protagonist.