Reimi Itsushiro hails from a distinguished family, her parents being accomplished opera singers based overseas. She shares her home with Aoi, a part-time maid and music student who serves as an older sister figure. Physically striking with purple eyes and waist-length blonde hair, she typically dresses in a school uniform complete with a ribbon tie and tights.

As an apprentice healer at the Karasuma Voice Healing Clinic, she trains alongside fellow students Kana Fujii and Hibiki Morishima. Reimi’s driving force is her profound admiration for Ria Karasuma, the clinic’s celebrated director, spurring her to seek closeness and meticulously imitate her mentor. She exhibits a headstrong, determined personality that sets her apart from the other apprentices.

A pivotal moment arises when upheaval—including temporary expulsion from the clinic and new internships—prompts her to cut her long hair short. This act marks her shift toward forging her own identity as a healer, distinct from emulating Ria. Through diligent work with Kana and Hibiki, she ultimately earns her C-Level healer certification, solidifying her growth into a recognized practitioner of vocal medicine.