Originally named Lazuli, Android 18 is a human transformed into a cyborg by Dr. Gero of the Red Ribbon Army, alongside her twin brother Android 17. This modification granted her superhuman abilities powered by a perpetual energy reactor, including flight, strength, speed, durability, energy projection, and inexhaustible stamina. Her cellular enhancements preserved biological functions, enabling her to later bear a child. Designed for Gero's vendetta against Goku, she and her brother rebelled, killing Gero shortly after activation. Unlike her ruthless alternate future counterpart, she showed no interest in indiscriminate violence and gradually allied with the Z-Fighters.
Her relationship with Krillin developed after he spared her life by destroying her remote deactivator during the Cell Saga. They married and had a daughter, Marron. As a wife and mother, she maintains a pragmatic focus on financial stability, often encouraging Krillin to compete in tournaments for prize money. Her personality blends stoicism with dry sarcasm, coupled with protectiveness toward her family. She retains a confident, no-nonsense demeanor in confrontations and remains unafraid to use force when necessary, such as threatening Mr. Satan for greater compensation.
In *Dragon Ball Super: Super Hero*, she participates as reinforcement against the Red Ribbon Army's bio-weapon, Cell Max. Piccolo avoids involving her or Android 17 initially due to concerns that Dr. Hedo, Gero's grandson, could exploit their cybernetic weaknesses. She arrives with Krillin, Goten, Trunks, and Bulma during the final battle against Cell Max. Her presence underscores her ongoing role as a reliable ally in Earth's defense.
Her design evolves across appearances, featuring distinct outfits like a denim vest and skirt or a cowgirl ensemble, later shifting to practical attire such as jeans, boots, and a tracksuit. For the Universe Survival Saga, she wears a pink tracksuit with gray shoes. Consistent visual traits include blonde hair, blue eyes, and gold hoop earrings.
Throughout her development, she transitions from a morally ambiguous antagonist to a core member of the Z-Fighters, balancing her roles as a fighter, spouse, and parent while retaining her trademark assertiveness and wit.