Apep, the serpentine god of chaos and evil, declares himself the archenemy of Ra, the sun god. He repeatedly attempts to disrupt Ra's travels, but these efforts consistently fail as Ra either ignores or remains entirely unaware of Apep's presence. During one ambush, Apep emerges from the sea sensing Ra nearby yet cannot locate him, resulting in Ra's boat harmlessly sliding off Apep's head as the journey continues uninterrupted. This pattern establishes Apep as an ineffectual antagonist whose actions yield no tangible success.

Physically, Apep towers over other deities, standing approximately three times Ra's height. His design includes distinctive eyes depicted as either golden irises or perpetually closed. He maintains a serpentine form aligned with his mythological origins, often accompanied by personified chaos entities portrayed as small black mooks. His appearance occurs briefly during the initial episode's explosion sequence caused by Medjed, placing him among the deities affected by the event.

Apep embodies the conceptual force of chaos within the story's cosmology. His characterization emphasizes comedic futility over genuine threat, contrasting with traditional Egyptian mythology where he represented a serious adversarial force. This manifests through repeated failures: his attacks never succeed, his presence goes unacknowledged, and he cannot compel recognition from Ra. In one narrative instance during a Season 2 episode, multiple deities disguise themselves as Apep's chaos entities using paper-thin disguises that retain their identifiable physical traits.

No significant character development or backstory expansion occurs for Apep beyond these traits. His appearances reinforce his static role as a persistent but harmless source of comedic antagonism, contributing to the series' lighthearted tone through ongoing, unresolved conflict with an oblivious opponent.