Kano Ienaga, born Chikanobu in Mikawa province (modern-day Aichi Prefecture) and assigned male at birth, escaped Abashiri Prison. She transitioned and presented as a woman, consistently identified and addressed as female by others, including those aware of her past. She possessed striking beauty, featuring black hair typically tied in a bun, long eyelashes, full red lips, and a mole on her lower lip. Meticulous grooming maintained her youthful look until Sugimoto's criticism of her self-delusion about her youth caused wrinkles to appear around her eyes. Her attire often included a long black Edwardian dress with embroidered flowers and a necklace. After capture by the 7th Division, she frequently wore a white medical coat. Ienaga owned and operated the Sapporo World Hotel as a front. A trained, renowned doctor, she perverted her medical expertise into torturing and dismembering victims to consume body parts she deemed desirable. This cannibalism arose from a twisted interpretation of Chinese medicinal diets, applied to humans to preserve youth and beauty. She showed no remorse. Her personality blended surface-level politeness and formality with deep narcissism and a fixation on physical appearance. She valued aesthetics above all, coldly exploiting victims for their attributes. An admirer of the arts, she connected with figures like counterfeiter Chouan Kumagishi through an art dealer. Her motivations were complicated by trauma from her mother's failed abortion, fueling an obsession with motherhood as an unattainable ideal of "perfection." During the Murder Hotel Arc, Ienaga attempted to kill guests, including Sugimoto's group and Ushiyama. Her hotel was destroyed by fire. Rescued by Ushiyama, she joined Hijikata Toshizō’s faction. She provided medical expertise, logistical support like cooking, and identified Kumagishi as a resource for verifying tattooed skins. Her medical skills, including complex surgeries like trepanation, proved valuable. Following her capture by the 7th Division, she intermittently aided both allies and enemies as a medic. Her character development culminated in sacrificing herself to save the pregnant Inkarmat during a confrontation with Tsukishima. Injecting Tsukishima with a sedative to delay him, she was fatally shot. She expressed fulfillment in enabling Inkarmat to achieve motherhood, viewing it as "perfection." Her death scene included symbolic imagery of blood forming wings and a halo. Ienaga’s portrayal features controversial links to harmful tropes: her transition and violence are intertwined, echoing real-life serial killers like H.H. Holmes (inspired by her "murder hotel") and Ed Gein (reflected in her body-part obsessions). This connection between her transgender identity and villainy perpetuates stereotypes historically used to marginalize transgender people. Her abilities included exceptional surgical knowledge and cooking proficiency. She wielded knives and poison-tipped syringes as weapons.