Yasuhiko Shirabyoshi appears in the Black Jack OVA Clinical Chart 7: "Black and White," adapting manga chapter 160. He is the chief of surgery at Tozai University, occupying a prominent position within the medical establishment. Shirabyoshi has brown hair and eyes, appearing adult, and wears formal attire including a suit and tie.

His professional stance places him in direct opposition to unlicensed medical practitioners. Shirabyoshi participates in an International Medical Association panel debating whether to grant an international license to the underground surgeon Black Jack. During the proceedings, he formally objects to Black Jack's licensure, reflecting his adherence to conventional credentials and institutional protocols. This highlights ethical and professional tensions regarding unorthodox practitioners.

Shirabyoshi's personal life involves his fiancée, Catherine, who postpones their wedding to provide medical aid in a war-torn region. This occurs concurrently with his involvement in the medical licensure debate, though no direct causal link between these events is established.