Alessandro Pecchino was an elderly Italian politician who secured his place among the 160 individuals selected for the Medusa virus cryogenic sleep program through financial means rather than medical necessity. His background as a senator is noted. He maintained a gruff demeanor and consistently prioritized his own safety above others in the survivor group, displaying cowardly behavior. His distrustful nature manifested early when he identified Marco Owen as a criminal based on visible tattoos, instigating a clash that required physical intervention from Peter Stevens and Kasumi Ishiki. This established his tendency to create friction.

Characterized as stubborn and pessimistic, he frequently complained about their circumstances and resisted following the group's decisions, particularly those involving risky movement toward the facility's surface. His abrasive personality contributed to his status as an outsider. During the group's traversal of an underground flooded tunnel, he was viciously attacked and devoured alive by mutated eels, becoming the first casualty among the central survivors. His death received minimal mourning, reflecting his unpopularity.

In a later metaphysical sequence involving deceased characters, he appears alongside Katherine Turner and Peter Stevens. Within this non-corporeal context, he uttered a backhanded remark urging Marco to return to the living world and save Kasumi, suggesting a complex layer to his personality. His Italian nationality is consistent across all media. His portrayal remains consistent in other adaptations or spin-offs.