Misa Anehara, a 25-year-old programming student and pioneering modern magic practitioner, casts spells through computer code from her family’s repurposed magic school—a legacy of her grandfather. After her mother, Mayuri, introduced her to code-based sorcery in childhood, Misa embraced experimental spellcraft until Mayuri’s death during her brother Soshiro’s birth. Forced into guardianship, Misa accidentally infused Soshiro’s meals with magic, rendering him immune to enchantments.

Though whimsically eccentric—collecting oddities like banana hangers and bulk curry roux—Misa’s ingenuity surfaces in crisis. She coded the "Christmas Shopper" to infiltrate global networks and conjured a colossal teddy bear to halt a plummeting plane. Her magic often bends behavior for profit, prioritizing results over ethical nuance.

Soshiro oscillates between criticizing her impulsiveness and shielding her from consequences. As a mentor, Misa guides not only Koyomi Morishita, who stumbled into her world via an old flyer, but also Kaho Sakazaki, training the latter in modern magic despite Kaho’s blindness to supernatural forces. Childhood magical excesses left Misa with cryptic physical scars, while her appearance—green-haired, bespectacled, and curvaceous—sometimes shifts in hue across records.

Her sorcery rewrites spell algorithms, manipulates time, and lets her morph into "Ghostscript," a spectral memory imprint used to battle foes. In a defining gambit, she staged her own demise to exile a destructive sorceress into a dimensional void, balancing cunning with self-sacrifice. While media consistently frames her as a nexus between arcane traditions and digital innovation, her inner journey remains largely uncharted.