Mise Altoise is Agnes Boulange's mother and teacher, with their familial relationship revealed as the narrative unfolds. Visually characterized as an adult wearing distinctive glasses, she practices magic and the esoteric science of alchemy, involving transmutation and artifact creation. Her workshop becomes a destination for the main characters investigating abnormal Ale concentrations and meteor phenomena. Prior to their arrival, she departs to seek a significant artifact, leaving behind a letter for Agnes explaining her absence and mission. This quest-driven disappearance positions her as an indirect catalyst for later events involving artifact recovery and conflict resolution. Her alchemical expertise, established within the setting's magical framework, involves the manipulation of materials and energies.