Chika Oguie is a university student and a central figure in the narrative of Genshiken 2, joining the Society for the Study of Modern Visual Culture, known as Genshiken, after a difficult start to her college life. She hails from the Tohoku region in northeastern Japan and actively tries to suppress her regional accent while studying in Tokyo, though it tends to resurface when she is under stress. Physically, she is petite with short, dark hair often tied up in a spiky top-knot, though she occasionally wears it down. Chika has poor eyesight and requires corrective lenses, typically wearing contact lenses but sometimes using her old glasses as a form of disguise.

Upon her introduction, Chika is a self-professed otaku-hater who is full of self-loathing, a contradiction that stems from her own secret identity as a passionate fujoshi, or female fan of yaoi and boys' love manga. Her intense internal conflict is rooted in a traumatic incident from her junior high school years. At the behest of a friend, she created a yaoi doujinshi that featured a male classmate named Makita, with whom she had a secret romantic relationship. When he discovered the manga, the ensuing humiliation caused Makita to transfer schools, leaving Chika deeply traumatized and filled with shame over her interests. This past trauma manifests in extreme reactions, such as defensiveness and even attempting to flee from embarrassing situations, including jumping out of a window to escape humiliation. Her emotional guardedness is visually symbolized by her eyes, which initially lack reflective highlights, giving her a hostile and distant appearance.

Chika’s role in the story is significant, as her personal journey of self-acceptance forms a major narrative arc throughout Genshiken 2. She reluctantly joins the Genshiken club after leaving her university's Manga Society due to her unresolved trauma. Within the club, key relationships help her to grow and change. Kanji Sasahara, a fellow member, is particularly persistent in reaching out to her, and his patient and accepting nature allows Chika to slowly open up about her past. Their relationship deepens into a romance, and Sasahara becomes a supportive partner, even serving as a reference for her anatomically correct drawings, including explicit ones, which signifies her growing comfort with her fujoshi identity. She also forms close friendships with other club members, such as Saki Kasukabe, who gives her the nickname Ogichin, and Kanako Ohno, a fellow otaku who sometimes teases her but also encourages her to cosplay.

Throughout the series, Chika undergoes substantial development. She transitions from a cynical and emotionally closed-off individual to a more approachable and friendly person who openly embraces her hobbies. Her increasing emotional health and self-acceptance are reflected in her appearance, as she begins to dress in more stylish clothing and the previously dead look in her eyes gains light. Professionally, Chika is a highly skilled artist, and her talent leads her to secure a publishing contract with Monthly Afternoon, the same magazine that originally published the Genshiken manga. Her notable abilities include creating yaoi doujinshi under pen names like Ogino Naruyuki and Yukimian, with favorite series to parody including titles like Slam Dunk, Fullmetal Alchemist, and Code Geass. Her journey comes full circle when she takes on a leadership role, succeeding Ohno as the president of Genshiken, where she mentors new members and uses her art to recruit others to the club.