Nurse Joy operates Pokémon Centers across regions like Sinnoh, part of a vast family sharing her surname and identical appearance, distinguished only by the color of the plus symbol on their nursing caps. She heals and restores Pokémon with unwavering professionalism. In Sinnoh, she also judges Pokémon Contests and Grand Festivals alongside Raoul Contesta and Mr. Sukizo, showcasing expertise in both Pokémon physiology and contest criteria. Trainers bypassing her Center due to the new Cycling Road once shook her confidence. After voicing doubts, she regained self-assurance by guiding Brock through hatching his Pokémon Egg, which became a Happiny. She then helped battle Team Rocket when they attempted to steal the newly hatched Pokémon, returning to her duties with renewed dedication. Brock frequently makes romantic advances towards her, which she typically meets with polite confusion before Croagunk or companions remove him. A non-canonical dream sequence induced by a sleeping spell depicted multiple Nurse Joys expressing affection for Brock. While generally calm, she exhibits firmness confronting those who harm Pokémon, especially Team Rocket. Her Sinnoh design features Mexican-pink attire, a white apron, and flat Mary Jane shoes, consistent with her appearances in Kanto, Johto, and Hoenn. All Nurse Joys share identical vocal patterns.