Yayoi Orikura, a widow and mother of daughters Kana and Manami Orikura, lives in Akizuki City. When Yoshihiko Mizusawa's father faces a sudden transfer, she hosts Yoshihiko for his final month of high school, placing him under the same roof as her family.

She possesses grey hair and grey eyes, standing 1.66 meters tall and weighing 48 kilograms, with measurements of 84-59-86. Her blood type is AB, and she practices medicine as a doctor (医師).