Indy Yakko appears in the "Kama Sutra" anime narrative as a comedic adventurer involved in archaeology. His background establishes him as good-natured and parodies established adventure archetypes, incorporating elements reminiscent of Go Nagai's recurring self-insert devices. Within "Kama Sutra," he assists Professor Takeshi Aikawa, participating in the rescue of Ryu Aikawa and others from antagonists like Prince Rudra. His key actions include skilled driving during pursuits, aiding escapes from physical traps, using concealed tracking devices to locate captured allies, and joining the climactic journey to the mythical Shambala. During an escape from a crushing wall trap, he disables an electrical system unconventionally. Following the Shambala confrontation, he returns alongside Ryu.

Beyond "Kama Sutra," the character manifests in other Go Nagai works. In "Zuba-Ban," he appears as Chief Geroyakko, a supernaturally strong Native American character originating from tribal conflicts in America. His background involves wandering battlefields before journeying to Japan while pursuing a buffalo. Within this narrative, he allies with protagonists against the Hyakki Klan, fulfilling a comic relief role despite his formidable strength.

A minor appearance occurs in "Shutendoji," where a character named Tokolov Yakkolavski is listed among the crew members aboard the spaceship Alfard during a 21st-century space mission. This iteration does not significantly contribute to the plot and perishes alongside most crew when the ship is destroyed upon returning to Earth.

Additionally, in "Omorai-kun," a version named Hiyayakko (Cold Tofu) is depicted as a university graduate beginning his career as a school teacher. Tasked with managing a problematic student named Omorai, his efforts focus on understanding the student's unconventional living situation, though his approach yields limited success in resolving the underlying issues.