Jō Anno is the head of the Hero Department at the Saitama headquarters of the Earth Defense Force. He serves as the maternal uncle of the protagonist, Retto Enjō, and is a scientist responsible for the maintenance of the H×EROS devices and the development of the XERO suits used by the heroes.

Personality-wise, Jō is depicted as a cheerful and easygoing individual who prefers to dress in relaxed, flashy, and extravagant clothing. He possesses a somewhat peculiar set of ethics but is also a skilled cook. Despite his flamboyant demeanor, he demonstrates a rational and sensible side. For instance, he successfully convinced the strict superiors and the formal Tokyo headquarters to allow the protection of the alien character Chacha, arguing that doing so was crucial for understanding Kiseichuu biology.

In terms of his role and relationships, Jō Anno acts as the chief of the Saitama branch and gives Retto Enjō permission to assist in the fight against the Kiseichuu. He is aware of details regarding Retto's past and serves as a key figure who understands and supports him. His position becomes critical during a crisis when the governor, Mogana Iwatsu, is arrested for violating an ordinance, which threatens the dissolution of the Saitama headquarters. It is later revealed that the governor was actually the Kiseichuu Queen, and after this discovery, the threat to the headquarters is resolved.

Regarding his notable abilities, Jō is not a frontline combatant but a support specialist. His primary role is as a scientist who maintains the heroes' equipment and develops the technology they rely on. His capabilities lie in his strategic thinking, his ability to navigate bureaucratic systems to protect his team, and his understanding of the enemy's biology. No specific information is available about any significant personal development or changing arc for this character across the course of the story.