Shūichiro Takanashi, a university lecturer immersed in researching the "Stone of Life," pursues mastery over the artifact’s power to manipulate reanimation and immortality. Outwardly principled, he conceals a merciless dedication to his experiments, sacrificing ethics and allies alike to advance his goals. His theft of the Stone from Euphrosyne Studion—a reanimated noblewoman—is executed through calculated manipulation of Sayaka Kamoshida, a graduate student ensnared by romantic devotion to him.

Securing the Stone, Shūichiro subjects his sister, Mako Takanashi, to a radical experiment by implanting the artifact into her body. The procedure grants her immortality and heightened physical prowess, but intensifies her volatile, destructive impulses. Their relationship thrives on a twisted symbiosis: Shūichiro coldly assesses Mako as a specimen, while she harbors a warped loyalty that fractures when his experiments trigger uncontrollable violence. During a chaotic confrontation, Mako retaliates by fatally tearing out his heart, abruptly ending his reign of manipulation.

Shūichiro’s methodology reveals a chilling pragmatism. He euthanizes and reanimates a dog to test the Stone’s limits, exemplifying his dismissal of moral constraints. His pursuits stem from a fusion of obsessive scientific ambition and nihilistic conviction, valuing breakthrough over human consequence. Though his death halts his direct influence, the aftermath reverberates through Mako’s unleashed carnage and the escalating conflict surrounding the Stone of Life.