Keisuke Honda is portrayed as a highly skilled and dedicated soccer player, recognized as an important member of the Japanese National Football Team and renowned as a deadball specialist, mirroring his real-life reputation. His fictionalized version, developed with input from the real Honda based on his experience and philosophy, features as "another main character" alongside the protagonist, not merely a cameo.

Positioned as the Japanese National Team's "secret weapon" for an exhibition match against Real Madrid, his participation becomes uncertain due to a significant pre-match injury, creating narrative tension about his availability and recovery timeline. On the field, Honda demonstrates exceptional strategic abilities. He visualizes the soccer field like a star chart, enabling him to calculate optimal positioning, passing trajectories, and scoring opportunities through spatial awareness and foresight, a skill shared with other top players in the series.

His skills are depicted as comparable to protagonist Teppei Sakamoto, establishing him as a formidable presence crucial to the team's efforts against elite competition in high-stakes matches. Honda's primary narrative arc centers on his recovery from injury juxtaposed with his determination to compete for the national team, reflecting themes of overcoming physical adversity and managing self-doubt against superior opponents.