Enzo operates as an opportunistic information broker and undertaker within New York’s shadowy underworld, capitalizing on tragedies such as mass suicides to expand his funeral enterprise. He trades critical intelligence with Bayonetta, securing favors like managing high-profile funerals while discreetly siphoning profits from their deals. Though their partnership remains strictly transactional, he reliably furnishes pivotal leads, such as guiding her to Vigrid for insights into the Eyes of the World.

A portly figure marked by a Brooklyn drawl, long sideburns, and a ponytail, Enzo’s flamboyant style shifts with his fortunes. Early appearances feature a green coat, red scarf, and black suit adorned with rings and a hat, later transitioning to a purple coat, white scarf, and pink-striped shirt as his circumstances evolve.

Brash and profit-driven, Enzo peppers conversations with curses and vents frustration over relentless misfortunes—angels sabotaging his schemes, Bayonetta wrecking his car—yet beneath his abrasive exterior lies devotion to his children, Ed and Edna. After the Homunculi invasion obliterates his family, grief overrides his greed, reshaping his priorities toward survival and protection of his remaining loved ones.

His misadventures frequently collide with supernatural chaos. After organizing a funeral for "Eggman the Destroyer," he flees angelic assaults, his car reduced to wreckage. Though he grumbles about escorting Bayonetta to Fimbulventr to track Inferno’s gates or enduring holiday shopping interrupted by celestial attacks, he begrudgingly aids her missions, narrowly escaping peril each time.

Rooted in Italian heritage, Enzo references family traditions like his grandmother’s grappa, initially serving as a comic foil enduring slapstick humiliations. However, the destruction of his family and relentless brushes with danger reveal resilience, layering his once-cartoonish persona with grit and emotional complexity amid ceaseless turmoil.