Ise serves in M-Squad, a specialized anti-magical terrorism unit commanded by Colonel Yoshiaki Iizuka. His unwavering dedication to the squad dominates his life, eclipsing personal pursuits and sharpening his combat resolve. Known for merciless efficiency, he nearly executes the mercenary Nazani during an operation, halted only by Asuka’s intervention.

He collaborates closely with M-Squad’s core members—Asuka, Kurumi, Shima, Yoshino, and Kaede—during perilous missions. One such operation against the Russian mafia, involving a dimensional bridge, sees him overwhelmed by Nazani’s retaliatory fireballs. This incapacitation reignites Asuka’s suppressed trauma over prior casualties, underscoring the high-risk nature of their assignments and Ise’s embedded role within the team’s dynamics.

His decisions prioritize mission success above all, often manifesting in lethal decisiveness against perceived threats. Interactions with fellow squad members remain strictly professional, adhering to military protocol and hierarchy, with little deviation into personal rapport.