Misae Kannazuki presides as headmistress over the high school division of St. Cherine Academy. She is the grandmother of Aoi Kannazuki, one of the current Twin Angels. In her own youth, Misae actively served as a Twin Angel alongside her sister, Sakie Kannazuki, establishing her legacy within the magical girl lineage of a previous generation. Her position involves overseeing the academy where the present Twin Angels, including her granddaughter Aoi, study. This background as a former Twin Angel connects directly to the series' themes of legacy and generational heroism, embodied by Aoi continuing the family's role as the Blue Angel.