Madara-san is a second-year high school student and president of the Chemistry Club. She possesses long black hair reaching her lower back, yellowish-brown eyes, and notably sharp pointed teeth. Her standard outfit includes black eyeglasses and a white lab coat worn over her school uniform—a pinkish-white dress shirt, navy blue pleated knee-length skirt, black pantyhose, and red slippers.

Shy yet morally strict, she reacts strongly to perceived impropriety. After overhearing phrases like "Pull it out!" during a magic trick rehearsal between Sempai and Assistant, she misinterprets the context as indecent and demands an end to such "shameless" activities before permitting Assistant to join her club.

Scientifically adept with extensive physics and chemistry knowledge, Madara-san enjoys demonstrating principles through experiment-based tricks resembling magic. She openly disdains stage magic as fraudulent deception, causing friction with the Magic Club when her science demonstrations are compared to Sempai's illusions.

In later manga chapters, including Chapter 53, she continues showcasing science-rooted tricks but bristles when Sempai equates them to magic, consistently reinforcing her stance on science's distinction from illusion. Her interactions center on Chemistry Club activities, experiments, and opposition to the Magic Club.