Mitsuki manifests as distinct characters across multiple stories in the anthology.

In the "No Longer Human" adaptation, she works as a prostitute in a brothel, forming a profound connection with the alienated protagonist Yozo. Amidst his self-destructive turmoil, she offers steadfast kindness and empathy. Despite personal adversity, she clings to optimism, determined to amass savings for escape and renewal. Her supportive presence anchors Yozo's narrative until his actions precipitate her tragic demise.

In "In the Forest, Under Cherries in Full Bloom," Mitsuki emerges as a beautiful yet imperious woman encountered by the bandit Shigemaru. Upon marrying him, she compels him into serial murder to satiate her desires, wielding bloodthirsty manipulation. Her morbid fascinations and psychological dominion over Shigemaru fuel his violent trajectory.

In "Hell Screen," Mitsuki is Yoshihide’s daughter. Her father, disillusioned by societal suffering under the king, sacrifices her to complete his masterpiece—a painting exposing the realm’s true horrors. Her fate underscores the human cost of artistic obsession.