Hitomi is a second-generation Bioroid, a genetically engineered organic being designed with suppressed aggressive tendencies and an inability to experience hatred or destructive emotions. Created through artificial insemination and rapid incubation, she emerged with advanced education in political sciences, which facilitated her swift rise to Vice Minister of Olympus. Her regulated emotional state results in a typically cheerful and childlike personality, though she exhibits intellectual curiosity about human emotions—particularly love—while finding human expressions of hatred disturbing and irrational. Despite a biological age potentially as young as ten to twenty years, her accelerated development grants her the physical appearance of a woman in her mid-to-late twenties. Functioning as a headhunter for Olympus's elite counter-terrorism unit E-S.W.A.T., Hitomi specializes in recruiting personnel from the post-apocalyptic wastelands. Her missions include rescuing and integrating key figures such as Deunan Knute and Briareos Hecatonchires into Olympus society, often assisting their acclimation to the city's utopian environment. She leads high-stakes operations like the extraction of Deunan from hostile territories and participates in crisis interventions such as thwarting hijackings or bio-terrorist threats. Biologically, Hitomi shares significant DNA with Carl Knute, making her a genetic relative of Deunan Knute. This connection becomes significant when antagonists exploit her unique genetic profile as a biological key to deactivate Gaia, Olympus's governing artificial intelligence, accessing secure systems. In another critical incident, her delayed enrollment in a life-extension program leaves her vulnerable after terrorists destroy the Bioroid reproductive data, necessitating the retrieval of the "Appleseed" data to reactivate her biological functions and save her life. Hitomi's character arc explores the tension between her engineered emotional limitations and her growing fascination with human experiences. She forms a close, quasi-friendship with Deunan, engaging in social activities like shopping trips. Her interactions highlight attempts to comprehend concepts like familial bonds, exemplified when she cares for an abandoned infant and contemplates whether her attachment mirrors human parental love. These moments underscore her role as a bridge between Bioroid logic and human emotional complexity. In broader conspiracies, Hitomi becomes a strategic pawn or target due to her administrative access and genetic traits. She is forcibly used in attempts to dismantle Olympus's infrastructure and later held hostage during a cyborg's fugitive investigation. Her knowledge proves pivotal during existential threats to Olympus, such as when she provides crucial access codes to disable autonomous weapon systems threatening the city's survival.