Oda Nobunaga emerges as a feudal warlord amid Japan's civil war era, driven to unify the nation and impose peace. He relies on protection from the heroic ninja trio—Akakage, Aokage, and Shirokage—who confront evil warlords, sorcerers, and monsters endangering his pursuit of order. His political influence attracts assassination attempts by antagonists like the Negoro ninja Kurayami Kidou and samurai lord Yuzato Dannojo, aiming to sabotage his unification campaign. This adversarial dynamic recurs prominently within the "Battle with Negoro Ninjas" story arc.

Portrayed by actors Kuraoka Shintarou and Shimada Keiitirou across segments of the original 1967–1968 series, his presence remains consistent. The 1987–1988 anime remake sustains this role throughout all 23 episodes.