Kayoko Huang commands Special Fire Force Company 6 as Battalion Commander and head surgeon, operating from Special Fire Fighting Defence Clinic 6 hospital. Born September 7 (Virgo) with AB blood type, she is 47 years old, 170 cm (5'7") tall, and weighs 55 kg (121 lbs). Her appearance features short black hair, light eyes, and long eyelashes. She typically wears the standard Special Fire Force jacket with metal neck protection, a waist-length cloak, a black dress, and high-heels instead of trousers. During medical procedures or combat, she adds a surgical mask and gloves; within her hospital, a white lab coat covers a dark shirt.
As a Third Generation pyrokinetic, her Ignition Ability manifests as an asklepian—a medical staff symbol. This power accelerates cell division to heal wounds, cure diseases, and alleviate symptoms. By synchronizing with their flames, she amplifies regeneration in other Third Generations and instantly eliminates pain. Her technique envelops patients in specialized flames, resembling cremation externally while repairing tissue damage internally. Her combat approach mirrors her medical methodology: she analyzes Infernals as "patients," dispatching them with precision-tailored tools.
Methodical and focused, she occasionally displays religious devotion, questioning if divine punishment influences events like Company 8's ventures into the Netherworld. She maintains a reserved demeanor, frequently expressing frustration over her heavy caseload yet remaining dedicated to treating injuries during joint operations with other Companies. Though willing to collaborate, she selectively withholds sensitive information, such as details about her Adolla-related experiences. A distinctive scar on her left palm resulted from Adolla energy contact during Shinra Kusakabe's surgery, a detail she later conceals during investigations.
Her involvement includes attending high-level meetings with Raffles III to discuss Adolla Burst and Spontaneous Human Combustion. She healed Shinra Kusakabe after a life-threatening chest injury from Haumea, accurately predicting his three-day recovery. At Hibana's request, she examined Konro's injuries, theorizing large-scale fires or mass deaths might trigger Adolla Links in non-Adolla Burst individuals—during which she omitted insights from her scarred hand. She coordinated disaster relief during the Second Great Cataclysm as her hospital reached capacity, later heeding Akitaru Ōbi's broadcast urging hope to counteract the Cataclysm's despair-based mechanics. Following Shinra's reality-altering reversal of the Cataclysm, she was restored to life.
The etymology of her name reflects her traits: "Kayoko" combines the characters for "fire," "generation," and "child," while "Huang" (黄) means "yellow," suggesting potential Chinese heritage.