Issa, known as Panda, is a stuffed panda-like creature and a member of the "Happy AniYoko Trio" alongside Iyo the rabbit and Kenta the bear. He self-identifies as "the empathic one." His core role involves striving to mediate conflicts between Iyo and Kenta, though his persistent peacemaking efforts often meet with limited success. Issa consistently shows kindness towards the human protagonist, Ami, and actively works to include her in the trio's activities.

Born on November 23, his zodiac sign is Sagittarius. He is three years old with blood type AB. Issa's character remains consistent across all documented manga, anime, and supplemental media appearances, maintaining his empathetic nature and peacekeeping role without significant evolution or additional backstory. His interactions focus on facilitating group harmony and nurturing a positive relationship with Ami.

His relationships are defined by his frequent interventions in Iyo and Kenta's arguments and his protective, considerate behavior toward Ami. Occasional dialogue suggests potential romantic feelings for Ami, though these remain unexplored. Issa arrived in Ami's room via the AniYoko door, with no provided information regarding his origins, family, or prior experiences. He undergoes no notable changes or milestones in any official storylines.