Dot Pyxis commands the Garrison Regiment's southern territory, encompassing Trost District, with supreme authority over defense. He bears a bald head, gold eyes, a distinctive mustache, and light, wrinkled skin. His standard uniform includes the Garrison attire layered over a white button-up shirt, a red sash edged in gold, and a purple bolo tie, consistent with other high-ranking officers. Pyxis exhibits an eccentric personality, maintaining a calm and light-hearted demeanor even in crises, famously quipping he wouldn't mind being eaten by a Titan if it were "a stunning beauty." Despite this, he operates as a pragmatic and effective leader. He comprehends soldiers' fears, permitting the overwhelmed to leave while persuading others to fight by invoking the safety of their families. A strategic risk-taker, he notably gambled on Eren Jaeger's Titan abilities to seal Wall Rose's breach at Trost. Pyxis openly admits his readiness to sacrifice humanity for its ultimate survival, declaring he would become a "butcher" if required. Unlike peers motivated by personal aims, his sole focus is humanity's advancement; he opposes any threat to its survival. During the Trost invasion, Pyxis intervened to stop Eren's execution after Armin Arlert argued his strategic worth. He devised the operation using Eren's Titan form to carry a boulder and seal the breached gate. Confronting mutiny from demoralized troops, he first falsely presented Eren as a government experiment, then offered deserters pardons. He ultimately convinced soldiers to stay by stressing their families' vulnerability. Pyxis oversaw the operation, authorizing continued sacrifices despite losses and deploying reinforcements upon success. When Wall Rose was allegedly breached again, Pyxis deduced no actual breach occurred due to minimal Titan presence. He collaborated with Erwin Smith to investigate, later discussing the theory that all Titans were once humans, with Titan Shifters differing only by retaining consciousness. During Erwin's plot against the corrupt royal government, Pyxis offered conditional support. He orchestrated a test by faking Wall Rose's breach: if nobles prioritized refugee lives, he would surrender; if they prioritized self-preservation, he would join the rebellion. The nobles' refusal to admit refugees led Pyxis to aid their arrest, facilitating Historia Reiss's coronation. Later, Pyxis attended the Survey Corps' departure to reclaim Shiganshina and participated in strategic discussions concerning Zeke Yeager's proposed alliance. After Zeke's spinal fluid transformed him into a Pure Titan during Marley's surprise attack on Shiganshina, Armin Arlelt killed him. Pyxis also appears in ancillary stories. In the OVA "The Sudden Visitor: The Torturous Curse of Youth," he judged a cooking contest between cadets Jean Kirschtein and Sasha Braus, declaring Jean's omelet the winner over Sasha's meat-centric dish. His role during the Trost operation in the compilation film *Attack on Titan Part 1: Guren no Yumiya* remains consistent with the anime.