Pandora, a principal antagonist in the *Saint Seiya* saga, stands as Hades’ sister in his mortal incarnation. A scion of Germany’s Heinstein nobility, her fate shifted irrevocably in childhood upon breaching a forbidden family vault to unseal Athena’s box, unleashing the twin deities Hypnos and Thanatos. Bound by their decree to safeguard Hades until his destined war, she traded unwavering service for immortality. When Hades’ awakening annihilated all life at Heinstein Castle save her own, she ascended as his devoted commander, overseeing his Specter forces. Her strategic ferocity emerged during Hades’ assault on the Sanctuary, exemplified by her brutal discipline of Wyvern Rhadamanthys. Yet her loyalty intertwined with complexity through Phoenix Ikki: years prior, she sought to claim Ikki’s brother Shun as Hades’ vessel, embedding a soul-linked pendant into Shun while erasing Ikki’s memory and disguising the artifact as a maternal gift. Decades later, during the Underworld war, she confronted Ikki anew. Struck by his unyielding will, she surrendered her interdimensional necklace to aid his journey to Elysion—a treasonous act that provoked Thanatos to execute her. In her final moments, color returned to her world as she perished in Ikki’s arms. The *Lost Canvas* spin-off amplifies her obsessive guardianship of Hades, depicting a paranoia-fueled arc. Tricked by Hypnos and Thanatos into sealing Hades’ soul to prioritize crafting the Lost Canvas, she intersects with Tenma, son of her childhood companion Partita. Consumed by misplaced vengeance, she condemned Partita for allegedly stealing Hades’ essence, later enduring psychological torture and a lethal duel with her former friend. Saved from death by Tenma’s intervention, she observed their climactic struggle before departing to challenge Alone, Hades’ corrupted vessel. Pandora wields divine artifacts bolstered by god-tier cosmic power, compensating for limited physical strength. Her arsenal includes a harp whose melodies inflict psychological torment, a serpent-conjuring ring, a trident unleashing destructive energy, and a necklace enabling cross-dimensional travel—transferred fatefully to Ikki. Her teleportation speed rivals Leo’s light-speed strikes, granting near-instantaneous movement. Spanning timelines, her narrative weaves threads of fanatical loyalty, divine manipulation, and fractured redemption, casting her as a tragic architect bridging mortal strife and celestial warfare within the *Saint Seiya* cosmos.