Kamijou Touma wields Imagine Breaker in his right hand, an ability negating all supernatural phenomena—magic, esper powers, divine blessings, and even his own luck—upon contact. This power classifies him as a Level 0 in Academy City despite its significance. Imagine Breaker serves as a "reference point" for the world, restoring distorted realities, though it cannot negate fundamental forces like life energy or ley lines. Severing the right arm releases a dangerous entity, often manifesting as dragon-like forms of varying colors and translucency, which figures like Fiamma of the Right and Aleister Crowley sought to exploit. This entity can overwhelm powerful adversaries but risks Touma's life due to severe bleeding, typically giving him approximately 10 minutes before fatal blood loss. The arm regenerates after each severance, with the mechanism unclear, and some evidence suggests multiple entities may reside within him.
Touma faced significant childhood ostracization outside Academy City, labeled a "god of pestilence" due to the misfortune attracted by Imagine Breaker. An assailant attempted to stab him, followed by media exploitation. His father enrolled him in Academy City hoping its scientific environment would mitigate superstitions, though Touma's letters home indicated persistent mistreatment. Aleister Crowley orchestrated this enrollment to integrate Imagine Breaker into his plans, inadvertently leading to the creation of Kazakiri Hyouka from the AIM diffusion fields' fear of the ability. Within Academy City, Tsukuyomi Komoe noted Touma displayed mischievous behavior in his youth. His classmates value him for absorbing their collective misfortune but resent his unintentional appeal to females, dubbed the "Kami-yan disease" by Tsuchimikado Motoharu.
A defining incident occurred when Touma intervened in Mitsuari Ayu's suicide attempt at Ground Geo but dropped his phone during a collision with Shokuhou Misaki, delaying the rescue. He later prevented Misaki from erasing her own memories. After shielding her from Deadlock, Touma suffered anterograde amnesia specific to her, forgetting new interactions while retaining pre-incident memories. His first encounter with Misaka Mikoto involved rescuing her from thugs, though she required no assistance. This pattern established his reputation for attracting female attention, though he avoids romantic commitments despite expressing a preference for "dorm manager onee-san types" like Kanzaki Kaori.
During the Index Arc, Touma destroyed Index's Walking Church while testing her claims of magic, triggering her ire. He later saved her from Stiyl Magnus and Kanzaki Kaori, who aimed to erase her memories annually to prevent brain overload. In doing so, he negated a memory-bound curse but suffered amnesia when a stray magical feather struck his head. He concealed this memory loss from Index to spare her guilt, confiding only in Heaven Canceller and later allies like Mikoto and Misaki, deepening his involvement with magic-related conflicts.
Touma consistently prioritizes others' safety over his own, declaring "I don’t need a reason to save someone." He acts impulsively, often sustaining severe injuries requiring hospitalization. His resolve remains unshaken even after memory loss, as his core beliefs persist. However, post-Baggage City events eroded his trust in others, fearing manipulation through his actions. He overcame this during a confrontation with Leivinia Birdway, reaffirming his commitment to helping those in need. Allies and adversaries characterize his self-sacrificial nature as "insanity." Accelerator and Leivinia note his combat "precognition"—a subconscious ability to predict attacks through environmental cues and involuntary movements. This skill falters if overanalyzed or when opponents restrict informational tells, as demonstrated by Rensa.
He engages female combatants like Sherry Cromwell or Vento of the Front if they endanger innocents, though his poorly chosen words often provoke Index’s bites or Mikoto’s lightning bolts. His catchphrases include "Such misfortune!" (不幸だ!) lamenting his luck, and "I will destroy that illusion of yours!" during decisive battles. Both phrases faded from use in New Testament but resurfaced after confronting Othinus.
In World War III, Fiamma severed Touma’s right arm to absorb Imagine Breaker, prompting an "invisible thing" to emerge and terrify Fiamma. Touma rejected its power, crushing it to regenerate his arm and reclaim Imagine Breaker. Later, during Othinus’s Omega World arc, he succumbed to despair in a "perfected" reality where his struggles held no meaning, attempting suicide. The Will of the Misaka Network convinced him to reclaim his flawed world, leading to a battle where he hesitated to destroy Othinus’s creation but ultimately conceded to her. Post-recovery, he resumed using his signature catchphrases.
On December 24th, Anna Sprengel force-fed Touma a black pill containing an enhanced St. Germain virus. Infected and dying by December 25th, he reached an understanding with the virus, allowing St. Germain to temporarily control his body against Anna. St. Germain later sacrificed himself by converging the microbes into Imagine Breaker, purging the infection.
Touma’s family includes his parents, Kamijou Touya and Shiina, who live outside Academy City, and a cousin, Otohime Tatsugami. His spiky black hair results from hair gel, not natural growth. He typically wears his school uniform with an orange T-shirt underneath and a white hoodie in winter, leading some to mistake him for a delinquent.