Shoko Ieiri functions as Tokyo Jujutsu High's primary physician. She holds a valid medical license earned by legitimately passing the national examination, though her eligibility to take the exam was falsified. Her surname is inspired by the television series *House, M.D.*, reflecting her medical position. As a student in 2006 alongside Satoru Gojo and Suguru Geto, she maintained neutrality during their frequent arguments, often physically distancing herself from confrontations. She exhibited a casual attitude during this time, smoking publicly despite her high school status and assisting Gojo in testing new techniques. After graduation, she transitioned into her medical role, adopting a more professional appearance: long brown hair sometimes tied in a ponytail, a mole beneath her right eye, and persistent dark circles under her eyes stemming from her demanding workload. Her typical attire is a white lab coat over a blue turtleneck sweater, navy pants, and cream-colored heels. Her personality is defined by a consistently laid-back and stoic demeanor, contrasting with colleagues like Kiyotaka Ijichi. She approaches medical duties with professionalism, compartmentalizing personal emotions during critical tasks like autopsies or treating severe injuries. She resumed smoking after a five-year hiatus, citing stress and nostalgia for her school days, and is recognized as the heaviest drinker within her circle, disliking sweets while favoring alcohol as both her preferred food and hobby. She remains politically neutral within Jujutsu society, aligning informally with Gojo due to their long friendship rather than institutional loyalty. Her most significant ability is the Reverse Cursed Technique (*Hanten Jutsushiki*), converting negative cursed energy into positive energy for healing. Unlike most sorcerers who can only self-heal, she outputs positive energy to regenerate others' lost limbs and severe wounds, a rare capability shared only by Yuta Okkotsu and Sukuna. She cannot verbally explain the technique's mechanics, limiting its teachability. While not combat-oriented, her student missions with Gojo and Geto imply foundational combat skills. Her medical expertise extends beyond healing; she conducts autopsies to analyze cursed phenomena, identifying Mahito's transfigured humans as modified humans and predicting the fatal brain effects of the Culling Game's technique-removal penalty. Key story involvements include healing Nanami after his battle with Mahito, treating Ijichi and Ino during the Shibuya Incident where she established an emergency medical station despite personal risk, agreeing to conceal Yuji Itadori's revival per Gojo's request, confirming the nature of Mahito's victims to alleviate Yuji's guilt, explaining cursed technique removal to Maki and Ijichi ahead of the Culling Game, collaborating with Yuta to heal Hana Kurusu for Gojo's extraction from the Prison Realm, informing Gojo of Nanami's death before his battle with Sukuna, and monitoring the Shinjuku showdown where she observed Gojo's declining cursed energy output before his defeat. She later received his body via Ui Ui's teleportation. Her character design features black hair and eyes in the manga, adapted to dark brown in the anime. She ranked between 23rd and 27th in the series' popularity polls.