Yuji Itadori, a high school student gifted with extraordinary physical prowess, leads an ordinary life until his grandfather Wasuke’s dying wish—to "help others" and die surrounded by comrades—anchors his purpose. This conviction propels him to ingest a cursed finger housing Ryomen Sukuna, a primordial curse, shielding his peers and binding the spirit to his body. Marked as Sukuna’s vessel, he faces eventual execution once all fingers are consumed. His lineage intertwines with centuries of manipulation: born to Jin Itadori and Kaori Itadori, his existence was engineered by Kenjaku, an ancient sorcerer who possessed Kaori to orchestrate Yuji’s birth. Jin, the reincarnation of Sukuna’s twin brother—devoured in the womb—forges a blood tie between Yuji and Sukuna, crafting a vessel to fully harness the curse’s power. This heritage links him to Choso and the Death Paintings, hybrid siblings birthed through Kenjaku’s prior experiments. Enrolled at Tokyo Jujutsu High, Yuji trains under Satoru Gojo, mastering cursed energy to augment his superhuman agility and strength. He channels this power into martial disciplines like Taido and techniques such as the destabilizing Divergent Fist and reality-warping Black Flash. Hosting Sukuna also grants him the rare ability to perceive soul boundaries, a skill pivotal in clashes with the soul-twisting curse Mahito. Trauma reshapes his path. The Shibuya Incident fractures his resolve when Sukuna briefly overtakes his body, slaughtering innocents. Losses of mentors Kento Nanami and Nobara Kugisaki compound his guilt, warping his identity from protector to a sacrificial "cog" in the jujutsu system. He embraces a hardened pragmatism, bearing responsibility for Sukuna’s carnage while dedicating himself solely to eradicating curses. Sukuna’s possession of Megumi Fushiguro ignites Yuji’s vow to destroy the curse and reclaim his friend. He endures grueling training, sacrifices flesh to mimic Sukuna’s abilities, and confronts his engineered origins. A climactic domain clash with Sukuna plunges Yuji into the curse’s tormented past, fostering unexpected empathy for their shared existence as vessels. This revelation reframes his worldview: life’s worth stems from lived moments, not death’s circumstances. His body bears the toll—scars from Mahito’s assaults, severed fingers from battles, fading Sukuna markings post-separation. Bonds shift from spirited alliances with Megumi and Nobara to a fractured kinship with Choso and tactical rapport with Aoi Todo. Through relentless loss, his resolve endures, steered by his grandfather’s creed and the drive to atone for Sukuna’s legacy, one relentless fight at a time.