Ana Coppola, an eleven-year-old girl originally from Cornwall, England, relocated to Japan during kindergarten and has lived there ever since with her family. Her entire education occurred in Japan, resulting in deep cultural immersion. This led to a near-total loss of her native English fluency and an exceptional understanding of Japanese traditions, vocabulary, and kanji surpassing many native peers, knowledge she initially tries to hide.

Her appearance distinctly reflects her English heritage: silky blonde hair, clear blue eyes, pale skin, and notably slender long legs. She frequently wears lavender or white clothing. This physical difference, especially her light hair among dark-haired classmates, causes significant self-consciousness, heightened by comments like Nobue Ito's persistent remarks about her developing chest.

Ana exhibits a personality marked by sophistication, politeness, affluence, and impeccable manners. Peers recognize her good fashion taste and well-mannered demeanor. However, she harbors insecurities about her name and heritage. Teasing about her surname "Coppola" resembling a Japanese psychomime (onomatopoeic for psychological/bodily states) at her previous school prompted her transfer. Determined to avoid further mockery, she pretends to speak only English upon entering her new class, introducing herself with simple English sentences despite her limited proficiency.

This pretense collapses almost immediately. An ingrained habit surfaces when she instinctively helps Matsuri Sakuragi open a door, addressing her in fluent Japanese and revealing her true ability, forcing her to abandon the facade. This incident leads her to walk home with Matsuri, accompanied by Miu Matsuoka and Chika Ito, and visit Chika's house, forming the foundation of her close friendships with these three girls.

Her surname remains a recurring source of irritation, primarily due to Miu's relentless teasing. Miu frequently calls her "Coppola-chan," knowing it annoys Ana. The teasing escalates when Miu interprets Ana's name using the kanji 穴骨洞 (meaning "hole," "bone," "cave"), provoking visible anger in Ana each time.

Within her friendships, Ana displays loyalty and kindness, though her relationship with Miu is often strained by the name-calling and Miu's antics. She lives in a large, Western-style house with a proper lawn and a fancy gate-buzzer, reflecting her family's wealth. She owns a yellow Labrador retriever named Frusciante, whom Miu nicknames "Fu-chan."

Regarding preferences, she nearly expresses a liking for traditional Japanese foods like natto or miso soup but ultimately states her preference is for Chika's cookies. She explicitly dislikes broccoli and tomatoes.

In the spin-off "Shugo Chara! Believe In Yourself!", Ana possesses a Guardian Character named Coppy, representing her desire to speak English fluently. Character Changing with Coppy grants her English fluency and calmness, marked by pink glowing strawberry hairclips, though it can also lead to frustration. Her ability to see Guardian Characters stems from being born with an egg. In this setting, her politeness attracts attention from boys, resulting in occasional love letters. Baron attempts to send her one, thwarted by Yaya's jealousy. She interacts with characters like Amu Hinamori, Hikari Yagami, Matsuri, and Miu, and experiences a blush-inducing moment with Marucho Marukura after holding hands.