Ami Kakei works as an assistant at manga studio G-PRO, focusing on finishing work and fashion elements, specializing in the "kakeami" cross-hatching technique referenced in her name. She possesses waist-length black hair, usually with bangs tied up by a yellow bead atop her head, and murky-green eyes.

Her expressions and speech typically convey a flat, uninterested demeanor, except when experiencing surprise or fear. Despite this outward detachment, she actively engages in wordplay and humor, creating manga-related puns like "Mango" (Manga master), "Mankin" (Manga muscle), and "Manchiku" (Manga fanatic). She keeps her own secrets, including her undisclosed pen name as a mangaka.

She frequents the vintage clothing store "Marriott Lunch Market" (also called "Mario's used clothing shop"), showcasing her unconventional fashion sense through unique garments acquired there. Aspiring beyond her assistant role, she aims to become a horror manga artist.

Following the main story, specifically after Kakushi Gotō's memories return, she transitions to working as an assistant for Rasuna Sumita, continuing her career in the manga industry. Her relationships center on professional interactions at G-PRO and her patronage of the vintage clothing store.