Dr. Serene (Dra. Serena in some regions) is a scientist on the Astro Lab team. She provides expertise in environmental and technological solutions for Team Astro's missions. Working alongside Professor Elefun and Dr. Blunt, she assists in developing inventions and strategies for disaster prevention and ecological conservation. Her technical skills involve creating specialized systems, such as repurposing irrigation equipment to divert volcanic lava and engineering a device to stabilize soil against sandstorms to combat desertification.

During one incident, her homemade meatballs were used to alter an asteroid's trajectory and prevent an Earth collision. She manages experimental projects, including a rapidly growing ivy species that overran the lab, necessitating team intervention. Her professional collaborations include supporting Dr. Blunt during the rescue of miniaturized team members he accidentally ingested and managing interpersonal challenges like Dr. Blunt's fear of the octopus Simone. No background, origin story, character development across seasons, or appearances in other media beyond this series are documented.