Amidst the Terrigen Mist crisis, Janet van Dyne embraces her role as the Wasp. She investigates the mutagen's distribution across Earth alongside Black Widow and Charade, targeting its source and orchestrators. The Wasp engages in delicate diplomacy between the Avengers and the Inhuman Royal Family concerning the Terrigen outbreak and its impact on new Inhumans. This includes contributing to plans for peaceful negotiations between human authorities and Attilan's rulers. She is not physically present at the crater site when critical talks unfold between Captain America, Iron Man, Black Bolt, and Medusa. These negotiations deteriorate into disaster following a World Security Council military incursion that frames the Avengers, sparking Inhuman accusations of betrayal. After the diplomatic failure and the Inhuman declaration of war against Earth, the Wasp continues her involvement in the escalating conflict, aiding the Avengers' strategic response to heightened tensions. She utilizes her signature abilities: size manipulation, flight via bio-synthetic wings, and firing bio-electric energy blasts. Her extensive experience as a long-tenured Avenger and former team leader guides her strategic perspective throughout these events.