"I Want to Eat Your Pancreas" is a manga adaptation of the novel by Yoru Sumino, illustrated by Idumi Kirihara. The story centers on an unnamed protagonist, a high school student who prefers solitude and keeps to himself. His life takes an unexpected turn when he discovers a handwritten journal in a hospital waiting room, belonging to his classmate, Sakura Yamauchi. The journal reveals that Sakura is suffering from a terminal pancreatic illness, a fact she has kept hidden from everyone except her family. Despite her condition, Sakura maintains a cheerful and outgoing demeanor, contrasting sharply with the protagonist's reserved nature.

Sakura approaches the protagonist after learning he knows her secret, and the two form an unlikely friendship. She insists on spending her remaining time with him, believing he will treat her normally rather than pity her. Over time, their interactions deepen, and the protagonist begins to open up, challenging his self-imposed isolation. Sakura’s vibrant personality and zest for life gradually influence him, while he provides her with a sense of normalcy and companionship.

The narrative explores themes of mortality, human connection, and the impact of fleeting relationships. Sakura’s illness looms over their time together, creating a poignant tension between the joy of their shared moments and the inevitability of her condition. The story also delves into the protagonist’s internal struggles, as he grapples with his emotions and the fear of losing someone he has grown to care about.

Tragedy strikes unexpectedly when Sakura dies not from her illness but in a random act of violence. Her death leaves the protagonist devastated, forcing him to confront his feelings and the meaning of their brief but profound relationship. The story concludes with him reflecting on their time together and how Sakura’s presence changed his perspective on life, relationships, and the importance of cherishing the present.

The manga captures the emotional depth of the original novel, with expressive artwork that complements the narrative’s tone. The characters are well-developed, with Sakura’s vivacity and the protagonist’s gradual transformation serving as the emotional core of the story. "I Want to Eat Your Pancreas" is a poignant exploration of love, loss, and the enduring impact of human connections.