"Eroko-san on the Attack" centers on Eroko, a high school girl who harbors a secret identity as a prolific erotic manga artist. Despite her innocent and reserved demeanor in daily life, Eroko channels her vivid imagination and bold creativity into her work, crafting stories that push boundaries and challenge societal norms. Her double life becomes increasingly complicated as she navigates the pressures of school, friendships, and her burgeoning career in the adult manga industry.

The narrative explores Eroko’s struggles to balance her personal and professional lives, often highlighting the contrast between her public persona and her private passion. Her classmates and teachers remain unaware of her alter ego, creating moments of tension and humor as she works to keep her identity hidden. Eroko’s dedication to her craft is unwavering, and she frequently draws inspiration from her surroundings, including her interactions with peers and her observations of human behavior.

Key characters include Eroko’s close friends, who provide emotional support and occasional comedic relief, as well as her editor, who plays a pivotal role in guiding her career and challenging her to grow as an artist. The series delves into themes of self-expression, creativity, and the challenges of pursuing an unconventional path in a society that often stigmatizes adult content. Through Eroko’s journey, the story examines the complexities of identity, ambition, and the pursuit of artistic fulfillment, all while maintaining a lighthearted and often humorous tone.