"How Do You Do, Koharu?" centers on Koharu, a young woman who works as a hostess at a high-end club. Her life takes an unexpected turn when she encounters a wealthy and enigmatic businessman named Kuga. Kuga, intrigued by Koharu’s unique personality and resilience, offers her a proposition: he will pay off her substantial debts in exchange for her companionship. Despite her initial reluctance, Koharu agrees, setting the stage for a complex relationship that blurs the lines between transactional arrangements and genuine emotional connection.

The narrative explores the dynamics of their relationship as Koharu navigates the challenges of her new life. Kuga’s cold and calculating demeanor contrasts sharply with Koharu’s warmth and determination, creating tension and growth between the two. As their bond deepens, Koharu begins to uncover Kuga’s vulnerabilities and the reasons behind his guarded nature. Simultaneously, Kuga finds himself drawn to Koharu’s authenticity, which challenges his cynical worldview.

Secondary characters, including Koharu’s colleagues at the club and Kuga’s business associates, add layers to the story, highlighting themes of ambition, loyalty, and societal expectations. The manga delves into the intricacies of power dynamics, personal agency, and the pursuit of happiness within a world shaped by wealth and privilege. Through its exploration of these themes, "How Do You Do, Koharu?" presents a nuanced portrayal of human relationships and the choices that define them.