"Cat in a Hot Girls' Dorm" centers around a young man named Kakeru, who, due to a series of unexpected circumstances, finds himself living in an all-girls dormitory. The premise begins with Kakeru’s grandfather, who owns the dormitory, imposing a condition that Kakeru must take care of a mysterious cat named Tama to inherit the property. Tama, however, is no ordinary cat; it possesses the ability to transform into a human girl, adding a supernatural twist to the story. This transformation ability complicates Kakeru’s life as he navigates the challenges of living in close quarters with the female residents while keeping Tama’s secret.

The dormitory is populated by a diverse group of female characters, each with distinct personalities and backgrounds. These include the diligent and responsible dorm manager, the mischievous and playful Tama in her human form, and other residents who contribute to the comedic and sometimes dramatic situations that arise. The interactions between Kakeru and the girls often lead to humorous misunderstandings, romantic tension, and moments of heartfelt connection.

The plot unfolds through a series of episodic events, blending comedy, romance, and light drama. Kakeru’s efforts to maintain Tama’s secret while managing his relationships with the dorm residents form the core of the narrative. The story explores themes of trust, responsibility, and the complexities of human relationships, all while maintaining a lighthearted tone. The balance between the supernatural element of Tama’s transformation and the everyday challenges of dorm life creates a unique dynamic that drives the series forward.