"Mama wa Poyopoyo-Saurus ga Osuki" centers on the daily life of a young boy named Sora and his mother, who has an unusual obsession with dinosaurs, particularly the fictional "Poyopoyo-Saurus." The mother’s enthusiasm for dinosaurs permeates every aspect of their household, from meals to decorations, often leading to humorous and chaotic situations. Sora, while initially embarrassed by his mother’s eccentric behavior, gradually comes to appreciate her unique personality and the warmth she brings to their family life.

The narrative unfolds through a series of episodic chapters, each highlighting the mother’s quirky antics and her attempts to share her love of dinosaurs with Sora and others around her. Her passion often results in creative, if unconventional, solutions to everyday problems, such as using dinosaur-themed games to teach life lessons or incorporating dinosaur motifs into her cooking. Despite the occasional misunderstandings or over-the-top moments, the mother’s actions are driven by genuine care and a desire to connect with her son.

Supporting characters include Sora’s classmates and teachers, who occasionally find themselves drawn into the mother’s dinosaur-centric world. These interactions provide additional comedic scenarios while also showcasing the mother’s ability to inspire and entertain those around her. The series balances humor with heartfelt moments, emphasizing the bond between Sora and his mother and the joy that comes from embracing individuality.

The manga’s tone is lighthearted and whimsical, with a focus on family dynamics and the small, often absurd, moments that make up daily life. Through its episodic structure, "Mama wa Poyopoyo-Saurus ga Osuki" explores themes of acceptance, creativity, and the importance of finding joy in the unconventional, all while maintaining a playful and engaging narrative.