"Go with the Clouds, North by Northwest" is a manga series set in Iceland, blending elements of mystery, slice-of-life, and supernatural intrigue. The protagonist, Kei Miyama, is a 17-year-old Japanese boy living in Reykjavik, where he works as a private investigator and driver. Kei possesses an unusual ability: he can communicate with cars, allowing him to understand their mechanical issues and even sense their "emotions." This skill aids him in his work, though it also isolates him from others, as he struggles to connect with people on a deeper level.

The narrative unfolds through episodic cases that Kei takes on, often involving missing persons, strange occurrences, or local mysteries. These cases serve as a vehicle to explore the unique Icelandic setting, its culture, and its folklore. The stories are often tinged with a sense of melancholy and introspection, reflecting Kei's internal struggles and his search for meaning in his life. His past is shrouded in mystery, with hints of a tragic event that led him to leave Japan and settle in Iceland.

Kei's relationships with other characters add depth to the story. His younger sister, Mizuki, occasionally visits him, providing glimpses into his family dynamics and his protective nature. Local characters, such as Lise, a café owner, and Einar, a mechanic, offer support and camaraderie, though Kei remains emotionally distant. The series also introduces supernatural elements subtly, with Icelandic myths and legends occasionally intersecting with Kei's investigations, blurring the line between reality and the fantastical.

The pacing is deliberate, emphasizing atmosphere and character development over action. The artwork complements the tone, with detailed depictions of Iceland's landscapes and a muted color palette that enhances the story's reflective mood. Themes of isolation, identity, and the search for connection are woven throughout, making "Go with the Clouds, North by Northwest" a contemplative and immersive reading experience.