"The Drops of God" is a manga series that intertwines the worlds of wine and personal legacy. The narrative centers on Shizuku Kanzaki, a young man who has spent his life distancing himself from his estranged father, Yutaka Kanzaki, a world-renowned wine critic. Upon Yutaka's death, Shizuku learns that his father has left behind a will with a peculiar challenge: to inherit the vast wine collection, Shizuku must identify and describe thirteen exceptional wines, referred to as the "Twelve Apostles" and the ultimate "Drops of God." Competing against him is Issei Tomine, a talented and ambitious young wine critic who was Yutaka's protégé.

The story unfolds as Shizuku, initially indifferent to wine, begins to explore its complexities, guided by his father's cryptic notes and the memories of their fractured relationship. Each volume delves into the discovery of one of the "Apostles," with the narrative blending detailed wine descriptions, historical context, and the emotional journeys of the characters. The series meticulously portrays the sensory experience of wine tasting, often using vivid metaphors and poetic language to convey the flavors and aromas.

As Shizuku and Issei race to uncover the wines, their rivalry evolves into a deeper understanding of their shared passion. The narrative also explores themes of family, legacy, and the transformative power of art, as both characters grapple with their personal histories and aspirations. Secondary characters, including wine producers, sommeliers, and enthusiasts, enrich the story, providing diverse perspectives on wine culture and its global significance.

The manga is notable for its educational approach, offering readers insights into wine varieties, regions, and tasting techniques. The plot is driven by the quest to identify the "Apostles," but it is equally propelled by the characters' growth and the intricate relationships they form. The series concludes with the revelation of the "Drops of God," a wine that embodies the pinnacle of Yutaka Kanzaki's legacy and the emotional resolution of Shizuku's journey.