"Alice & Zoroku" is a manga series that blends elements of science fiction, fantasy, and slice-of-life storytelling. The narrative centers around Sana Kashimura, a young girl who possesses extraordinary abilities known as "Dreams of Alice." These powers grant her the ability to manipulate reality, creating objects or altering her surroundings at will. Sana escapes from a secret research facility where she was held captive and experimented upon due to her abilities. During her escape, she encounters Zoroku Kashimura, a gruff but kind-hearted elderly man who runs a flower shop. Despite his initial reluctance, Zoroku takes Sana in, becoming her guardian and providing her with a sense of stability and family she has never known.

The story explores Sana's journey as she adjusts to life outside the confines of the research facility, navigating the challenges of everyday life while grappling with her powers and the moral implications of using them. Zoroku, a no-nonsense and pragmatic individual, serves as a grounding influence, teaching Sana about responsibility, empathy, and the importance of human connections. Their relationship evolves from one of reluctant caretaker and ward to a genuine familial bond, with Zoroku becoming a father figure to Sana.

As the series progresses, other characters with similar abilities, referred to as "Alice," are introduced, each with their own unique powers and struggles. These individuals often face societal rejection or exploitation due to their abilities, highlighting themes of isolation and the search for belonging. The narrative delves into the origins of the "Dreams of Alice," revealing a deeper connection between these powers and a mysterious phenomenon known as the "Witch's Tea Party." This event ties the fates of the Alice users together, creating a larger, interconnected story.

The series balances its fantastical elements with grounded, emotional storytelling, focusing on the personal growth of its characters. Sana's journey is one of self-discovery, as she learns to understand her powers, confront her past, and build a new life with Zoroku and the friends she makes along the way. The manga also explores themes of family, morality, and the consequences of wielding extraordinary abilities, presenting a thoughtful and engaging narrative that appeals to a wide audience.