"Kagamigami" is a supernatural action manga set in a world where humans coexist with spirits known as "kami." The story centers on Tsubasa, a young man who possesses the unique ability to see and interact with these spirits. Tsubasa works as a "kami exterminator," a specialized role tasked with eliminating malevolent spirits that threaten human lives. His abilities stem from a mysterious past tied to a powerful kami named Kyubi, a nine-tailed fox spirit that once wreaked havoc on the human world.

Tsubasa is joined by his partner, Ryudo, a skilled swordsman with a stoic demeanor, and a young girl named Asura, who harbors her own connection to the spirit world. Together, they form a team dedicated to protecting humanity from dangerous kami while uncovering the deeper mysteries surrounding their existence. The narrative explores the balance between humans and spirits, delving into themes of coexistence, morality, and the consequences of wielding supernatural power.

The plot unfolds as Tsubasa and his team encounter increasingly powerful and enigmatic spirits, each with their own agendas and ties to the human world. These encounters reveal fragments of Tsubasa's past, including his connection to Kyubi and the tragic events that shaped his life. As the story progresses, the team faces off against a shadowy organization seeking to exploit the power of kami for their own purposes, leading to high-stakes battles and moral dilemmas.

The manga blends action, mystery, and supernatural elements, with a focus on character development and the evolving dynamics between humans and spirits. Tsubasa's journey is marked by his struggle to reconcile his role as a protector with the darker aspects of his abilities, while Ryudo and Asura provide contrasting perspectives on the nature of power and responsibility. The narrative builds toward a climactic confrontation that challenges the characters' beliefs and forces them to confront the true nature of the kami and their place in the world.