Melissa Greenspan is an American actress who has built a career spanning both live-action television and voice acting for animation and video games. While she is known for recurring roles in primetime series such as Kim on Providence and Cindy on Desperate Housewives, her voice work constitutes a significant and long-running part of her professional activity.

Greenspan's voice acting career began in the 1990s with one of her earliest and most prominent roles in the animated series Doug. Between 1993 and 1999, she provided voices for several characters on the show, including Sally, Briar Langolier, and Cassandra Bleem. She later reprised the role of Briar Langolier for the 1999 feature film Doug's 1st Movie. In 2002, she voiced the character Sarah Wellington in The Wild Thornberrys Movie, another major animated production from the era. Her work in animation also extended to projects like Curious George 2: Follow That Monkey! in 2009, where she voiced a phone operator.

In the 2020s, Greenspan has continued to be active in voice acting, particularly in English-language dubs of anime. She is credited with the role of Hibari Torii in the Netflix original anime series The Way of the Househusband, which aired from 2021 to 2023. Her voice work in the series has been documented across multiple episodes. She also voiced the character Boco's mother in the 2023 Netflix original anime Gamera Rebirth and took on a role in the animated series Mr. Birchum in 2024. Beyond film and television, her voice can be heard in the video game Grand Theft Auto V, among others.

While Greenspan has worked on numerous projects, publicly available information does not prominently feature recurring collaborations with specific directors or voice actors. Her career is notable for its longevity and its balance between on-camera and voice acting roles, demonstrating her versatility as a performer. Her recent work in high-profile anime productions for streaming platforms highlights her continued presence in the voice acting industry.