Neil Patrick Harris is an American actor and performer who has contributed voice work to several English-language adaptations of anime projects. His involvement in this field is part of a broader career in television, film, and theater that began in the late 1980s. Prior to his work in anime, Harris had already established himself as a voice actor in Western animation, most notably providing the voice of Peter Parker in the 2003 animated series Spider-Man.

In 2021, Harris participated in two major anime releases for the streaming service Netflix. He voiced two distinct characters in the original net animation series Eden. In this science fiction series, set in a world inhabited by robots, he provided the English voice for the character Zero. Additionally, he voiced the role of Dr. Weston Fields in the same series. Also in 2021, he was part of the English voice cast for the Star Wars: Visions anthology series on Disney+. In the short film titled The Twins, produced by the animation studio Trigger, he voiced the character Karre, a powerful twin born of the dark side of the Force. His casting in these high-profile projects represents a notable foray into the medium of anime for a wide international audience.